Anti-CD33 Recombinant Antibody (TAB-756)

Customer Review

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David Walker
09.Sep,23

Ideal for CD33 Research

The Anti-CD33 Therapeutic Antibody (ZAMYL) has been excellent for our CD33 studies. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.

Emily Turner
11.Oct,22

Reliable in Immunoassays

We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for CD33 is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.

John Harris
20.Jul,21

Consistent and High-Quality

This antibody has proven to be consistent and high-quality in our assays. The reproducible results and strong affinity for CD33 have significantly improved our experiments, making it a crucial part of our research toolkit. The consistent performance has greatly enhanced our data quality.

Q&As

1. Is the anti-CD33 therapeutic antibody ZAMYL suitable for use in Western blotting?

   A: Yes, the anti-CD33 therapeutic antibody ZAMYL (TAB-756) is suitable for use in Western blotting. It provides specific binding to CD33, allowing for reliable detection in Western blot assays.

2. What are the storage recommendations for the anti-CD33 therapeutic antibody ZAMYL?

   A: The recommended storage condition for the anti-CD33 therapeutic antibody ZAMYL (TAB-756) is at -20°C or lower. For short-term storage, it can be kept at 2-8°C. To ensure stability, avoid repeated freeze-thaw cycles.

3. Can the anti-CD33 therapeutic antibody ZAMYL be used in flow cytometry analysis?

   A: Yes, the anti-CD33 therapeutic antibody ZAMYL (TAB-756) can be used in flow cytometry analysis. It is specifically designed to bind to CD33, making it suitable for detecting CD33-expressing cells in flow cytometry.

4. Is the anti-CD33 therapeutic antibody ZAMYL effective in immunoprecipitation assays?

   A: Yes, the anti-CD33 therapeutic antibody ZAMYL (TAB-756) is effective in immunoprecipitation assays. It provides specific binding to CD33, enabling its precipitation from complex mixtures for further analysis.

5. What is the optimal dilution for using the anti-CD33 therapeutic antibody ZAMYL in Western blotting?

   A: The optimal dilution for using the anti-CD33 therapeutic antibody ZAMYL (TAB-756) in Western blotting is typically 1:500 to 1:2000. It is advisable to perform a dilution series to determine the best working concentration for your specific experimental conditions.

View the frequently asked questions answered by Creative Biolabs Support.

Citations

1. Jiao, Rubin, et al. "A Theranostic Approach to Imaging and Treating Melanoma with 203Pb/212Pb-Labeled Antibody Targeting Melanin." Cancers 15.15 (2023): 3856. https://doi.org/10.3390/cancers15153856
   This study investigates a theranostic approach to imaging and treating melanoma by targeting melanin with radiolabeled antibodies. The researchers used a chimeric antibody, c8C3, labeled with two isotopes of lead: Lead-203 for SPECT imaging and Lead-212 for radioimmunotherapy. The study demonstrated that 203Pb-labeled c8C3 enabled effective imaging of melanoma tumors in mice, while 212Pb-labeled c8C3 significantly slowed tumor growth and improved survival rates without causing hematologic or systemic toxicity. This approach highlights the potential of using radiolabeled antibodies for both diagnostic and therapeutic purposes in melanoma treatment.
   Creative Biolabs provided the humanized anti-CD33 antibody lintuzumab (Cat# TAB-756) used as a negative control in this study. This antibody was crucial for validating the specificity and effectiveness of the melanin-targeting c8C3 antibody. The reliable performance of the lintuzumab antibody from Creative Biolabs ensured accurate control experiments, thereby supporting the overall conclusions regarding the therapeutic potential of the melanin-targeting radiolabeled antibodies.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-756, RRID: AB_3112003)

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Biosimilar Overview

Please refer to Lintuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Lintuzumab.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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Protocol & Troubleshooting

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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